李晓晖 教授
李晓晖,英国剑桥大学与中南大学联合培养博士,湘雅药学院药理学系教授,博士生导师,学科办主任。国际肺血管研究院(PVRI)委员,中国药理学会心血管专业委员会常务委员,中国生物工程学会转化医学专业委员会委员,湖南省药理学会治疗药物监测研究(TDM)专委会委员,复杂基质样本生物分析湖南省重点实验室副主任,湖南省药物评价创新产业联盟副秘书长,长沙市药物评价创新产业联盟副理事长。2014年中南大学“升华育英”计划入选者,2016年中南大学“创新驱动”计划获得者,2017年湖南省“湖湘青年英才”获得者,2018年长沙市首批高层次人才。主要研究领域为心血管药理与临床药理学,发表SCI论文52篇,参编专著1本,申请专利25项,主持国家自然科学基金面上项目、青年基金,湖南省重点研发计划,中国博士后基金特别资助等科研基金20余项。
联系邮箱:xiaohuili@csu.edu.cn
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代表性论文10篇
(1) Li WQ,Z H,Li XH*(并列通讯作者), Cai JF,Li D,Du J,Zhang BK,Xiang DX,Li NS,Li YJ* , CGRP derived from cardiac fibroblasts is an endogenous suppressor of cardiac fibrosis.Cardiovasc Res. 2019.08.28
(2) Wang J,Tian XT,Peng ZYF,Li WQ,Cao YY ,Li XH*(通讯作者).HMGB1/TLR4 promotes hypoxic pulmonary hypertension via suppressing BMPR2 signaling.Vasc Pharmacol.2019.01.03(117): 35-44.
(3) Xiang LL,Li Y,Deng X,Djuro Kosanovic, Ralph Theo Schermuly,Li XH*(通讯作者).Natural Plant Products in Treatment of Pulmonary Arterial Hypertension.Pulm Circ.2018.06.05, (8): 3.
(4) Yang YM,Du J, Liu F, Wang XY,Li XH*(并列通讯作者),Li YJ. Role of caspase-3/E-cadherin in helicobacter pylori-induced apoptosis of gastric epithelial cells.Oncotarget,2017.7.22, 8 (35): 59204-59216.
(5) He J,Li XH(并列第一),Luo H,Li T, Zhao L,Qi Q,Liu Y,Yu Z. Galectin-3 mediates the pulmonary arterial hypertension-induced right ventricular remodeling through interacting with NADPH oxidase 4.J Am Soc Hypertens.2017; 11(5):275-289.
(6) Deng B, Du J, Hu R, Wang AP, Wu WH, Hu CP, Li YJ,Li XH*(通讯作者).MicroRNA-103/107 is involved in hypoxia-induced proliferation of pulmonary arterial smooth muscle cells by targeting HIF-1β.Life Sci.2016; 147:117-124.
(7) Li Y,Li XH(并列第一),Huang ZJ,Tang XH,Liu JJ,Yuan H(*).Metoprolol restores expression and vasodilatation function of AT2R in spontaneously hypertensive rats.J Cardiovasc pharm,2014.03.12, 63(3): 252~258.
(8) Li XW, Du J, Hu GY, Hu CP, Li D, Li YJ,Li XH*(通讯作者).Fluorofenidone attenuates vascular remodeling in hypoxia-induced pulmonary hypertension of rats.Can J Physiol Pharmacol. 2014;92(1):58-69.
(9) Yang J,Li XH(并列第一),Li Y, Southwood M, Ye L, Long L, Al-Lamki RS, Morrell NW. Id proteins are critical downstream effectors of BMP signaling in human pulmonary arterial smooth muscle cells.Am J Physiol Lung Cell Mol Physiol. 2013; 305(4):L312-21.
(10) Yang J,Li XH(并列第一),Al-Lamki R,Wu C,Weiss A,Berk J,Schermuly RT,Morrell NW. Sildenafil Potentiates Bone Morphogenetic Protein Signaling in Pulmonary Arterial Smooth Muscle Cells and in Experimental Pulmonary Hypertension.Arterioscler Thromb Vasc Biol.2013; 33(1):34-42.