余鹏，博士，副教授，中南大学湘雅药学院硕士研究生导师。主要研究方向为生物分子识别的机制研究及应用开发，发表高水平学术论文300余篇，其中以第一作者/通讯作者发表56篇，申请专利28项，已授权7项，主持及参与国家、省、市等各级科研项目22项，指导学生获奖22项。

联系方式：

手机：13348716587

电子邮箱：peng.yu@csu.edu.cn

近5年承担课题：

1. 湖南省自然科学基金——科药联合基金基于核酸适配体的手性药物拆分方法的理论可行性研究（2022JJ80105）。执行年限：2022.1-2024.12.

2. 湖南省自然科学基金项目，基于生物质谱法定量耐药细胞转运蛋白表达量的方法建立及其在检测肿瘤细胞耐药指数上的应用（2018JJ2415）。执行年限：2018.1-2020.1.

3. 2018年师生共创立项项目，癌症个体化用药技术平台-基于人工智能的精准给药（2018gczd032）。执行年限：2018.11-2019.12.

近5年发表论文：

[1]Jie Y ,Xiaoling L ,Meilun C , et al.Non-immobilized GO-SELEX screening of aptamers against cyclosporine A and its application in a AuNPs colorimetric aptasensor.[J].Analytical methods : advancing methods and applications,2023, IF=3.1,JCR分区：Q2

[2]Yijie L ,Xiaoling L ,Meilun C , et al.Advances in screening, synthesis, modification, and biomedical applications of peptides and peptide aptamers.[J].BioFactors (Oxford, England),2023, IF=6.0,JCR分区：Q1

[3]Yijie L ,Jie Y ,Meilun C , et al.Recent advances in computer-aided virtual screening and docking optimization for aptamer.[J].Current topics in medicinal chemistry,2023,23(20):1985-2000.IF=3.041,JCR分区：Q1

[4]Hanbing J ,Jie Y ,Yucui H , et al.Evaluation of intracellular metabolism of methotrexate in hepatocytes and embryonic kidney cells based on Folylpolyglutamate Synthetase and gamma-Glutamyl Hydrolase expression.[J].Current drug metabolism,2023,24(2),IF=3.408,JCR分区：Q2

[5]Yucui H ,Xiaoling L ,Jie Y , et al.A label-free fluorescent aptamer sensor for testosterone based on SYBR Green I.[J].Analytical methods : advancing methods and applications,2023,15(12),IF=3.1,JCR分区：Q2

[6]Huanhuan Li, Tongji Cai, Yi Ren, Jing Huang, Hanbing Jiang, Yucui Hou, Chunhua Tang, Jie Yang, Jia Zhao，Peng Yu *. A simple unlabeled human chorionic gonadotropin biosensor based on a peptide aptamer. Analytical Methods，7 Sep 2021. doi: 10.1039/d1ay01105g. IF=2.596; JCR分区：Q2

[7]Zhonghua Ouyang , Jing Huang, Yi Ren, Huanhuan Li, Yao Ding, Ke Zhang, Lei Jiang, Peng Yu*.(2021).Studies on the intracellular accumulation process of methotrexate and its correlation with the key protein using an LC-MS/MS method: a novel way to realize prospective individualized medication.. Analytical and bioanalytical chemistry，Mar 2021, 413: 1799-1807. doi:10.1007/S00216-020-03125-2. IF=3.63; JCR分区：Q1

[8]Yi Ren, Yao Ding, Fanqi Meng, Lei Jiang, Huanhuan Li, Jing Huang, Peng Yu*, Zhaohui Qiu*. Quantification of CYP2E1 in rat liver by UPLC-MS/MS-based targeted proteomics assay: a novel approach for enzyme activity assessment. Analytical and bioanalytical chemistry，25 June 2020. doi:10.1007/s00216-020-02757-8. IF=3.637; JCR分区：Q1

[9]Huanhuan Li, Fanqi Meng, Lei Jiang, Zhaohui Qiu, Peng Yu*. Comparison of LC-MS/MS-based targeted proteomics and conventional analytical methods for monitoring breast cancer resistance protein expression. Life Sciences. 231(2019). IF= 3.448; JCR分区：Q1

[10]Lei Jiang, Fanqi Meng, Zhaohui Qiu, Ke Zhang, Yao Ding, Huanhuan Li, Yi Ren, Peng Yu*, Jie Peng. Comparison of UPLC-MS/MS-based targeted quantitation and conventional quantitative methods for the analysis of MRP1 expression in tumor cell lines. Journal of Chromatography B. 2019, 1109:10-18. IF= 2.813; JCR分区：Q2

近5年获批专利：

1. 余鹏、江寒冰、张可、丁尧；一种预测甲氨蝶呤药效的肽段组合物及其定量检测方法与检测试剂盒，2021.03.26，中国，ZL201911064881.2

2. 余鹏、李欢欢、孟凡奇、蒋蕾、任艺；甲氨蝶呤给药方案确定方法、装置、储存介质及设备，2019.05.14，中国，CN109754858A

3. 余鹏、蒋蕾、孟凡奇、丁尧；用于FPGS和GGH蛋白表达量检测的特征性多肽及其应用，2021.03.26，中国，ZL201910711103.1

4. 余鹏、蒋蕾、孟凡奇；一种估算齐多夫定药时曲线下面积的方法，2020.01.10，中国，CN110675961A